[1]吴 青,张永江,田欣哲*,等.以苄醇和亚铁氰化钾为原料的芳腈合成新方法研究[J].江西师范大学学报(自然科学版),2022,(01):87-92.[doi:10.16357/j.cnki.issn1000-5862.2022.01.12]
 WU Qing,ZHANG Yongjiang,TIAN Xinzhe*,et al.The Study on a New Method for the Synthesis of Aromatic Nitriles with Benzyl Alcohols and K4[Fe(CN)6] as the Raw Materials[J].Journal of Jiangxi Normal University:Natural Science Edition,2022,(01):87-92.[doi:10.16357/j.cnki.issn1000-5862.2022.01.12]
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以苄醇和亚铁氰化钾为原料的芳腈合成新方法研究()
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《江西师范大学学报》(自然科学版)[ISSN:1006-6977/CN:61-1281/TN]

卷:
期数:
2022年01期
页码:
87-92
栏目:
化学
出版日期:
2022-01-25

文章信息/Info

Title:
The Study on a New Method for the Synthesis of Aromatic Nitriles with Benzyl Alcohols and K4[Fe(CN)6] as the Raw Materials
文章编号:
1000-5862(2022)01-0087-06
作者:
吴 青1张永江2田欣哲3*郑先福3
1.洛阳市质量计量检测中心,河南 洛阳 471000; 2.河南中烟工业有限责任公司洛阳卷烟厂,河南 洛阳 471003; 3.河南农业大学理学院,河南 郑州 450002
Author(s):
WU Qing1ZHANG Yongjiang2TIAN Xinzhe3*ZHENG Xianfu3
1.Luoyang Testing Center for Quality and Measurement,Luoyang Henan 471000,China; 2.Luoyang Cigarette Factory of Henan Chinese Tobacco Industry Corporation Limited,Luoyang Henan 471000,China; 3.College of Science,Henan Agricultural University,Zhengzhou Henan 450002,China
关键词:
苄醇 亚铁氰化钾 氧化亚铜 芳腈
Keywords:
benzyl alcohols potassium ferrocyanide cuprous oxide aromatic nitriles
分类号:
O 621
DOI:
10.16357/j.cnki.issn1000-5862.2022.01.12
文献标志码:
A
摘要:
该文以Cu2O为催化剂,实现了苄醇与亚铁氰化钾的新反应,为芳腈的合成提供了一种经济有效的新方法.该方法优化了溶剂、催化剂、温度、氧气压强等反应条件,并在最佳反应条件下合成了16个芳腈化合物,分离产率为62%~87%.该文提出了该反应的机理:苄醇首先发生需氧氧化脱氢生成芳基甲醛,然后转化为芳腈.与文献报道的方法相比,该方法使用的反应物苄醇价格更便宜,且Cu2O为多相催化剂,重复使用性能良好,降低了反应成本.
Abstract:
The new economic and effective method for the synthesis of aromatic nitriles is found via the realization of a new reaction between benzyl alcohols with K4[Fe(CN)6] using Cu2O as the catalyst.The reaction conditions such as solvent,catalyst,temperature and oxygen pressure are optimized,and sixteen aromatic nitriles are synthesized under the optimum reaction conditions,in which the isolated yields are 62%—87%.The reaction mechanism is proposed that Benzyl alcohols undergo the aerobic oxidative dehydrogenation,followed by the conversion of aryl formaldehyde into aryl nitriles.Compared with the related methods,the substrates are replaced by cheaper benzyl alcohols.Moreover,the used catalyst Cu2O is a heterogeneous catalyst that can be recycled,which obviously decreases the reaction cost.

参考文献/References:

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备注/Memo

备注/Memo:
收稿日期:2021-05-05
基金项目:国家自然科学基金(21603060),河南省自然科学基金(212300410358)和河南省科技攻关课题(212102310372)资助项目.
通信作者:田欣哲(1977—),女,河南平顶山人,副教授,博士,主要从事有机合成方法学的研究.E-mail:zzutxz@126.com
更新日期/Last Update: 2022-01-25