[1]顾成浩,王涛,唐小丽,等.基于室温条件及无金属催化的多组分反应构建4-氨基-2-烷基-6-苯基-5-腈基嘧啶分子骨架[J].江西师范大学学报(自然科学版),2016,40(02):174-178.
 GU Chenghao,WANG Tao,TANG Xiaoli,et al.The Room-Temperature Metal-Free Muticomponent Synthesis of 4-Amino-2-Alkylsulfanyl-6-Aryl-5-Cyanopyrimidines[J].Journal of Jiangxi Normal University:Natural Science Edition,2016,40(02):174-178.
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基于室温条件及无金属催化的多组分反应构建4-氨基-2-烷基-6-苯基-5-腈基嘧啶分子骨架()
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《江西师范大学学报》(自然科学版)[ISSN:1006-6977/CN:61-1281/TN]

卷:
40
期数:
2016年02期
页码:
174-178
栏目:
出版日期:
2016-03-25

文章信息/Info

Title:
The Room-Temperature Metal-Free Muticomponent Synthesis of 4-Amino-2-Alkylsulfanyl-6-Aryl-5-Cyanopyrimidines
作者:
顾成浩;王涛;唐小丽;徐亮;余义开;李柔
江西师范大学化学化工学院,江西 南昌 330022
Author(s):
GU ChenghaoWANG TaoTANG XiaoliXU LiangYU YikaiLI Rou
College of Chemistry and Chemical Engineering,Jiangxi Normal University,Nanchang Jiangxi 330022,China
关键词:
多组分反应 室温 无金属 嘧啶
Keywords:
multicomponent reactions room temperature metal-free pyrimidine
分类号:
O 626
文献标志码:
A
摘要:
以硫脲、苯甲醛、丙二腈和溴代脂肪烃为原料,在无金属催化及室温条件下,建立了可以较高产率制备4-氨基-2-烷基-6-苯基-5-腈基嘧啶等嘧啶环系列化合物的4组分合成新方法,所得的合成新方法具有良好的普适性以及进一步推广应用的潜力.
Abstract:
New four-component tandem reactions of malononitrile,halohydrocarbon,thiourea and aromatic aldehyde have been successfully developed only at room temperature and under metal-free conditions,in good to excellent yields of 4-amino-6-aryl-5-cyanopyrimidines.

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备注/Memo

备注/Memo:
基金项目:国家自然科学基金(21262018)资助项目.
更新日期/Last Update: 1900-01-01