[1]张小兰,汪秋英,吕英英,等.微波辐射下N-取代-1,8-萘内酰亚胺的合成研究[J].江西师范大学学报(自然科学版),2013,(06):603-606.
 ZHANG Xiao-lan,WANG Qiu-ying,Lü Ying-ying,et al.The Research on Microwave-Assisted Synthesis of N-Alkyl-1H-Benzo [c , d] Indol-2-Ones[J].Journal of Jiangxi Normal University:Natural Science Edition,2013,(06):603-606.
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微波辐射下N-取代-1,8-萘内酰亚胺的合成研究()
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《江西师范大学学报》(自然科学版)[ISSN:1006-6977/CN:61-1281/TN]

卷:
期数:
2013年06期
页码:
603-606
栏目:
出版日期:
2013-12-31

文章信息/Info

Title:
The Research on Microwave-Assisted Synthesis of N-Alkyl-1H-Benzo [c , d] Indol-2-Ones
作者:
张小兰;汪秋英;吕英英;高兆芬;郑大贵
上饶师范学院江西省普通高校应用有机化学重点实验室,江西上饶,334001;江西师范大学化学化工学院,江西南昌,330022
Author(s):
ZHANG Xiao-lan;WANG Qiu-ying;Lü Ying-ying;GAO Zhao-fen;ZHENG Da-gui
关键词:
N-取代-18-萘内酰亚胺卤代物N-烷基化反应微波辐射合成
Keywords:
N-substotuted-1H-benzo [cd] indol-2-onehalogenated compoundN-alkylationmicrowave irradiationsynthesis
分类号:
O624.6
文献标志码:
A
摘要:
在微波辐射和氢化钠促进下,1,8-萘内酰亚胺和卤代物在N,N-二甲基甲酰胺中经N-烷基化反应合成了N-取代-1,8-萘内酰亚胺衍生物,反应在6 ~8 min内完成,产率为87; ~93;.该方法具有产率高、反应时间短、操作简便等优点.所有产物经核磁氢谱、红外光谱和元素分析表征.
Abstract:
A series of N-alkyl-1H-benzo[c,d]indol-2-ones were synthesized by N-alkylation reactions of 1H-benzo[c,d]indol-2-one and halogenated compounds in N,N-dimethylformamide in the presence of sodium hydride under microwave irradiation.The reactions were completed with 87%~95% yields in 6~8 min,and this procedure has the advantages such as high yields,short reaction time and easy work-up.The target compounds were confirmed by their H NMR,IR and elemental analysis.

参考文献/References:

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备注/Memo

备注/Memo:
江西省普通高校重点实验室科技计划(GJJ10733)
更新日期/Last Update: 1900-01-01