参考文献/References:
[1] 焦诗卉,何淼.HIV辅助受体CCR5常见小分子抑制剂抑制效果的综合评价 [J].中山大学学报:自然科学版,2012,51(6):97-102.
[2] Mohsen Shahaei,Alireza Pourhossein.Modeling of CCR5 antagonists as anti HIV agents using combined genetic algorithm and adaptive neuro-fuzzy inference system(GA-ANFIS)[J].Med Chem Res,2013,22(9):4423-4436.
[3] Mohammed Abdul Rasheed,Nagul Meera Shaik,Nirogl R.Concise and aimple synthesis of M1 allosteric agonist TBPB [J].Synthetic Communications,2013,43(13):1796-1801.
[4] Ji Yongjun,Shu Mao,Lin Yong,et al.Combined 3D-QSAR modeling and molecular docking study on azacycles CCR5 antagonists [J].Journal of Molecular Structure,2013,1045(3):35-41.
[5] Renato Skerlj,Gary Bridger,Zhou Yuanxi,et al.Design and synthesis of pyridin-2-ylmethylaminopiperidin-1-ylbutyl amide CCR5 antagonists that are potent inhibitors of M-tropic(R5)HIV-1 replication [J].Bioorganic & Medicinal Chemistry Letters,2011,21(23):6950-6954.
[6] Lavina Gharu,Rajesh Ringe,Jayanta Bhattacharya.HIV-1 clade C envelopes obtained from late stage symptomatic Indian patients varied in their ability towards relative CD4 usages and sensitivity to CCR5 antagonist TAK-779 [J].Virus Research,2011,158(1):216-224.
[7] Lu Shoufu,Chen Binglong,Dave Davey,et al.CCR5 receptor antagonists:Discovery and SAR of novel 4-hydroxypiperidine derivatives [J].Bioorganic & Medicinal Chemistry Letters,2007,17(7):1883-1887.
[8] Richard R G,John F W W,Brown K,et al.1,3-dihydro-2,1,3-benzothiadiazol-2,2-diones and 3,4-dihydro-1H-2,1,3-benzothidiazin-2,2-diones as ligands for the NOP receptor [J].Bioorganic & Medicinal Chemistry Letters,2004,14(20):5045-5050.
[9] Paul E F,Bryan O,Sander G M.Antagonists of the human CCR5 receptor as anti-HIV-1 agents.Part 4:Synthesis and structure-activity relationships for 1-[N-(methyl)-N-(phenylsulfonyl)amino]-2-(phenyl)-4-(4-(N-(alkyl)-N-(benzyloxycarbonyl)amino)piperidin-1-yl)butanes [J].Bioorganic & Medicinal Chemistry Letters,2001,11(18):2475-2479.
[10] Christopher K A,Saheem A Z,Zhang Zhu,et al.Design syntheses,and characterization of pharmacophore based chemokine receptor CCR5 antagonists as anti prostate cancer agents [J].European Journal of Medicinal Chemistry,2013,69:647-658.
[11] Mark A Ashwell,Jean-Marc Lapierre,Alan Kaplan.The design preparation and SAR of novel small molecule sodium(Na)channel blockers [J].Bioorganic & Medicinal Chemistry Letters,2004,14(9):2025-2030.
[12] 王涛,黄海金,罗劲,等.2E-3-苯基丙烯酰氧基烃基膦酸二乙酯的合成与生物活性研究 [J].江西师范大学学报:自然科学版,2011,35(1):15-17.
[13] 汪淼.CCR5受体拮抗剂的设计、合成与生物活性研究 [D].沈阳:沈阳药科大学,2009.