[1]韩新宁,李继凯,白晓朝,等.一次性塑料餐具中尼泊金酯迁移量的测定[J].江西师范大学学报(自然科学版),2021,(04):438-441.[doi:10.16357/j.cnki.issn1000-5862.2021.04.19]
　HAN Xinning,LI Jikai,BAI Xiaochao,et al.The Determination of the Migration of Parabens in Disposable Plastic Tableware[J].Journal of Jiangxi Normal University:Natural Science Edition,2021,(04):438-441.[doi:10.16357/j.cnki.issn1000-5862.2021.04.19]
点击复制

一次性塑料餐具中尼泊金酯迁移量的测定()
分享到：

《江西师范大学学报》（自然科学版）[ISSN:1006-6977/CN:61-1281/TN]

卷:
期数:
2021年04期
页码:
438-441
栏目:
化学
出版日期:
2021-08-10

文章信息/Info

Title:
The Determination of the Migration of Parabens in Disposable Plastic Tableware
文章编号:
1000-5862(2021)04-0438-04
作者:
韩新宁1; 李继凯1; 白晓朝1; 曹江平1*; 解启龙2*
1.宁夏师范学院化学化工学院,六盘山资源工程技术研究中心,宁夏 固原 756000; 2.中国科学院山西煤炭化学研究所煤转化国家重点实验室,山西 太原 030001
Author(s):
HAN Xinning1; LI Jikai1; BAI Xiaochao1; CAO Jiangping1*; XIE Qilong2*
1.Engineering and Technology Research Center of Liupanshan Resources,College of Chemistry and Chemical Engineering,Ningxia Normal University,Guyuan Ningxia 756000,China; 2.State Key Laboratory of Coal Conversion,Institute of Coal Chemistry,Chinese Academy of Sciences,Taiyuan Shanxi 030001,China
关键词:
一次性塑料餐具;  尼泊金酯;  迁移量
Keywords:
disposable plastic tableware;  parabens;  migration
分类号:
O 657
DOI:
10.16357/j.cnki.issn1000-5862.2021.04.19
文献标志码:
A
摘要:
该文建立了RP-HPLC法快速测定一次性塑料餐具中尼泊金甲酯、尼泊金乙酯、尼泊金丙酯、尼泊金丁酯和尼泊金异辛酯迁移量的方法.优化了色谱分离和分析条件,采用Diamonsil C18(150 mm×4.6 mm×5 μm)色谱柱分离,用甲醇-水体系梯度洗脱,检测波长为254 nm,流速为1.0 mL·min-1,柱温为30 ℃.该方法的线性范围为5～1 000 ng·mL-1(R>0.99),检出限为0.37～0.52 ng·mL-1,重现性良好,日内及日间重复测定的相对标准偏差分别为4.0%～5.3%、4.3%～7.5%.该方法成功应用于塑料杯、塑料碗、塑料盘等一次性塑料餐具中5种尼泊金酯迁移量的测定.
Abstract:
A rapid method for the simultaneous determination of the migration of methylparaben(MP),ethylparaben(EP),propylparaben(PP),butylparaben(BP)and octylparaben(OP)in disposable plastic tableware is developed by RP-HPLC.The chromatographic separation and analysis conditions are optimized.The separation is performed on a Diamonsil C18(150 mm×4.6 mm×5 μm)column with a gradient elution system of methanol-water.The detection wavelength is set at 254 nm,the flow rate is 1.0 mL·min-1,and the column temperature is 30 ℃.The linear range of this method is 5—100 ng·mL-1(R>0.99),the detection limit is 0.37—0.52 ng·mL-1,and the reproducibility is satisfactory.The relative standard deviations(RSDs)of intra-day and intra-day are 4.0%—5.3% and 4.3%—7.5%,respectively.The method is successfully applied to the determination of migration of five parabens in disposable plastic tableware such as plastic cup,bowl and plate.

参考文献/References:

[1] Soni M G,Carabin I G,Burdock G A.Safety assessment of esters of p-hydroxybenzoic acid(parabens)[J].Food and Chemical Toxicology,2005,43(7):985-1015.
[2] Giulivo M,Alda M,Capri E,et al.Human exposure to endocrine disrupting compounds:their role in reproductive systems,metabolic syndrome and breast cancer.A review [J].Environmental Research,2016,151:251-264.
[3] Nowak K,Ratajczak-Wrona W,Górsk M,et al.Parabens and their effects on the endocrine system [J].Molecular and Cellular Endocrinology,2018,474:238-251.
[4] Soni M G,Taylor S L,Greenberg N A,et al.Evaluation of the health aspects of methyl paraben:a review of the published literature [J].Food and Chemical Toxicology,2002,40(10):1335-1373.
[5] 肖晓峰,何军,刘艇飞,等.有机相阴离子交换固相萃取HPLC-UV法快速测定食品接触材料中4种尼泊金酯的特定迁移量 [J].分析测试学报,2018,37(4):471-476.
[6] 巫杨,孙倩,于昌平,等.水环境中尼泊金酯类防腐剂的赋存及生物降解研究进展 [J].环境化学,2018,37(8):1796-1803.
[7] Wróbel A,Gregoraszczuk E .Effect of parabens on estradiol secretion and CYP19 gene and protein expression in MCF-7 breast cancer and MCF-10A breast epithelial cells [J].Reproductive Biology,2013,13(1):36-37.
[8] Scsukova S,Rollerova E,Mlynarcikova A B.Impact of endocrine disrupting chemicals on onset and development of female reproductive disorders and hormone-related cancer [J].Reproductive Biology,2016,16(4):243-254.
[9] 国家卫生和计划生育委员会.GB 2760—2014 食品添加剂使用标准 [S].北京:中国标准出版社,2014.
[10] Yan Xiaohui,Zhong Dongdong,Zhan Yingying,et al.Porous polyimide particle-coated adsorptive microextraction bar combined with thermal desorption-gas chromatography for rapid determination of parabens in condiments [J].Journal of Chromatography A,2019,1601:71-78.
[11] Farajzadeh M A,Djozan D,Bakhtiyari R F.Use of a capillary tube for collecting an extraction solvent lighter than water after dispersive liquid-liquid microextraction and its application in the determination of parabens in different samples by gas chromatography:flame ionization detection [J].Talanta,2010,81(4/5):1360-1367.
[12] Shen Xiong,Liang Jian,Zheng Luxia,et al.Ultrasound-assisted dispersive liquid-liquid microextraction followed by gas chromatography-mass spectrometry for determination of parabens in human breast tumor and peripheral adipose tissue [J].Journal of Chromatography B,2018,1096:48-55.
[13] Cacho J I,Campillo N,Viñas P,Hernández-Córdoba M.Improved sensitivity gas chromatography-mass spectrometry determination of parabens in waters using ionic liquids [J].Talanta,2016,146:568-574.
[14] Azzouz A,Rascón A J,Ballesteros E.Simultaneous determination of parabens,alkylphenols,phenylphenols,bisphenol A and triclosan in human urine,blood and breast milk by continuous solid-phase extraction and gas chromatography-mass spectrometry [J].Journal of Pharmaceutical and Biomedical Analysis,2016,119:16-26.
[15] Yazdi M N,Yamini Y,Asiabi H.Fabrication of polypyrrole-silver nanocomposite for hollow fiber solid phase microextraction followed by HPLC/UV analysis for determination of parabens in water and beverages samples [J].Journal of Food Composition and Analysis,2018,74:18-26.[16] Makkliang F,Kanatharana P,Thavarungkul P,et al.A miniaturized monolith-MWCNTs-COOH multi-stir-rod microextractor device for trace parabens determination in cosmetic and personal care products [J].Talanta,2018,184:429-436.
[17] Blanco E,Casais M C,Mejuto M C,et al Combination of off-line solid-phase extraction and on-column sample stacking for sensitive determination of parabens and p-hydroxybenzoic acid in waters by non-aqueous capillary electrophoresis [J].Analytica Chimica Acta,2009,647(1):104-111.
[18] Alshana U,Ertas N,Gögˇer N G.Determination of parabens in human milk and other food samples by capillary electrophoresis after dispersive liquid-liquid microextraction with back-extraction [J].Food Chemistry,2015,181:1-8.
[19] Ye Xiaoyun,Bishop A M,Needham L L,et al.Automated on-line column-switching HPLC-MS/MS method with peak focusing for measuring parabens,triclosan,and other environmental phenols in human milk [J].Analytica Chimica Acta, 2008,622(1/2):150-156.
[20] 国家卫生和计划生育委员会.GB 31604.1—2015 食品接触材料及制品迁移试验通则 [S].北京:中国标准出版社,2015.
[21] 国家卫生和计划生育委员会.GB 5009.31—2016 食品中对羟基苯甲酸酯类的测定 [S].北京:中国标准出版社,2016.

备注/Memo

备注/Memo:
收稿日期:2020-01-25 本文其他作者:王超越,李洋洋,苏哈尔·胡安别克,叶正峰,李金花.
基金项目:宁夏自然科学基金(2020AAC03268),固原市科技计划(2020GYKYF005,2020GYKYF011),固原市人才课题(六盘山区中药材资源开发利用创新团队建设),宁夏重点研发计划(科技支撑)课题(2019BEG03071)和宁夏师范学院校级科研课题(NXSFZDB2111)资助项目.
通信作者:曹江平(1984—),男,陕西陇县人,讲师,主要从事样品处理、色谱基础及应用研
更新日期/Last Update: 2021-08-10