[1]刘冉彤,郑笑晨,金君,等.多壁碳纳米管-石墨烯复合膜修饰电极电化学检测异烟肼[J].江西师范大学学报(自然科学版),2014,(05):476-480.
　LIU Ran-tong,ZHENG Xiao-chen,JIN Jun,et al.The Electrochemical Detection of Isoniazid on a MWCNT/Graphene Composite Film Modified Electrode[J].Journal of Jiangxi Normal University:Natural Science Edition,2014,(05):476-480.
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多壁碳纳米管-石墨烯复合膜修饰电极电化学检测异烟肼()
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《江西师范大学学报》（自然科学版）[ISSN:1006-6977/CN:61-1281/TN]

卷:
期数:
2014年05期
页码:
476-480
栏目:
出版日期:
2014-10-31

文章信息/Info

Title:
The Electrochemical Detection of Isoniazid on a MWCNT/Graphene Composite Film Modified Electrode
作者:
刘冉彤;郑笑晨;金君;简选;于浩
延安大学化学与化工学院,陕西 延安,716000
Author(s):
LIU Ran-tong；ZHENG Xiao-chen；JIN Jun；JIAN Xuan；YU Hao
关键词:
多壁碳纳米管; 石墨烯; 化学修饰电极; 异烟肼
Keywords:
multi-walled carbon nanotube; graphene; chemically modified electrode; isoniazid
分类号:
O657.1
文献标志码:
A
摘要:
采用水合肼还原法制备了多壁碳纳米管（MWCNT）-石墨烯（GR）纳米复合物（MWCNT-GR），并采用滴涂法制备了此纳米复合物修饰的玻碳电极（MWCNT-GR/ GCE），研究了该修饰电极上异烟肼（Isonia-zid，INZ）的电化学行为.结果表明：在 pH 值为4.0的 HAc-NaAc 缓冲溶液中，异烟肼在0.35 V 处产生一灵敏的不可逆氧化峰.线性扫描伏安法测定异烟肼的线性范围为1.0×10-7~1.0×10-4 mol·L -1，检出限为5.0×10-8 mol·L -1（S/ N =3）.用该法测定了异烟肼注射液中异烟肼的含量，结果令人满意.
Abstract:
The multi-walled carbon nanotube / graphene composite(MWCNT-GR)were synthesized by using hydra-zine as a reduction agent. Based on this,a MWCNT-GR composite film modified glass carbon electrode(MWCNT-GR/ GCE)was fabricated. The electrochemical behavior of isoniazid(INZ)on this modified electrode was investi-gated carefully. The results showed that an irreversible oxidation peak at 0. 35 V of ING was observed on cyclic vol-tammograms in HAc-NaAc buffer solution(pH 4. 0). The linear range for determination of INZ by LSV was 1. 0 × 10 - 7 ~ 1. 0 × 10 - 4 mol·L - 1 with the detection limit of 5. 0 × 10 - 8 mol·L - 1(S / N = 3). Finally,this method was successfully employed to determine isoniazid in injection.

参考文献/References:

[1] 瞿万云,王宏,吴康兵.异烟肼在多壁碳纳米管修饰电极上的电化学行为及电化学测定 [J].分析化学研究简报,2005,33(10):1431-1434.
[2] Bikash K J,C Retna R.An nanoparticle decorated silicate network for the amperometric sensing of isoniazid [J].Talanta,2010,80:1653-1656.
[3] 吴春生.高效液相色谱-蒸发光散射检测器法同时测定烟肼丁醇片中盐酸乙胺丁醇和异烟肼含量 [J].中国药业,2013,22(19):38-40.
[4] 马明阳,吕九如.高碘酸钾-鲁米诺后化学发光的研究:流动注射——后化学发光法测定异烟肼 [J].分析科学学报,2007,23(1):13-16.
[5] Saeed S,Mandana A.Multi-walled carbon nanotube paste electrode for selectrue wltammetric detection of isoniazid [J].Microchim Acta,2007,157:149-158.
[6] Yang Gongjun,Wang Cunxiao,Zhang Rui,et al.Poly(amidosulfonic acid)modified glassy carbon electrode fordetermination of isoniazid in pharmaceuticals [J].Bioelectrochemistry,2008,73:37-42.
[7] Mir Reza M,Abolghasem J,Karim A Z.Voltammetric behavior and determination of isoniazid in pharmaceuticals by using overoxidized polypyrrole glassy carbon modified electrode [J].Journal of Electroanalytical Chemistry,2006,589:32-37.
[8] 简选,于浩,金君,等.聚L-组氨酸/石墨烯复合膜修饰电极对多巴胺和尿酸的同时测定 [J].江西师范大学学报:自然科学版,2013,37(3):32-37.
[9] 袁慧珍,宋永海,张梅,等.磷钼酸/壳聚糖功能化的石墨烯多层膜修饰电极及其电化学行为 [J].江西师范大学学报:自然科学版,2013,35(5):512-516.
[10] Seunghee W,Yang-Rae K,Taek D C,et al.Synthesis of a graphene-carbon nanotube composite and its electrochemical sensing of hydrogen peroxide [J].Electrochimica Acta,2012,59:509-514.
[11] 赵冬梅,李振伟,刘玲弟,等.石墨烯/碳纳米管复合材料的制备和应用进展 [J].化学学报,2014,72(2):185-200.
[12] William S H,Richard E O.Preparation of graphitic oxide [J].Journal of the American Chemical Society,1958,80(6):1339.
[13] 邱军,王建国,屈泽华,等.氧化处理方法与多壁碳纳米管表面羧基含量的关系 [J].新型碳材料,2006,21(3):270-272.
[14] 刘杨,崔屾,薛晓蕾,等.多壁碳纳米管的纯化研究 [J].化学研究与应用,2001,13(6):650-652.
[15] Wang Zhijuan,Zhou Xiaozhu,Zhang Juan,et al.Direct electrochemical reduction of single-layer graphene oxide and subsequent functionalization with glucose oxidase [J].Journal of Physical Chemistry,2009,113(32):14071-14075.
[16] Xia Haoyun,Hu Xiaoya.Determination of isoniazid using a gold electrode by differential pulse voltammetry [J].Analytical Letters,2005,38(9):1405-1414.

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备注/Memo

备注/Memo:
陕西省自然科学基金(2010JQ2005)
更新日期/Last Update: 1900-01-01